Pharmacological Approaches for Pain

Acute and chronic pain may be conceptualized as either nociceptive or neuropathic in origin. A broad description of the predominating pain pathophysiology can usually be inferred through: Patient description Physical findings Results of laboratory tests and imaging studies.There are several pharmacological interventions that may be accustomed manage pain in arthritis. However, in choosing the acceptable approach, the practitioner must take into account to consider the efficacy. Adverse side effects, dosing frequency, patient preference, and cost in choosing medication for pain management. When a patient develops the primary signs of an inflammatory arthritis, the most priority is symptom relief, with pain being the cardinal sign of inflammation that patients most wish facilitate with. However, it has become more and more clear that for inflammatory arthropathies like RA merely treating the symptoms with non- Steroidal anti- inflammatory drugs (NSAIDs) or analgesics in adequate, because features of the disease that lead to damage to the joints, and then to disability will carry on uncheck.  In addition to symptoms –relieving drugs, patients also need disease-modifying pain drugs that have been demonstrated to slow down or stop the damaging aspects of disease There are two aims in the pharmacological treatment; firstly to reduce inflammation or modulate the auto immune response and secondly to modulate the pain response. Medications is thought-about in 5 classes: simple analgesics, non-steroidal anti-inflammatory drugs (NSAIDs), Disease modifying anti-rheumatic-drugs (DMARD’S), Steroids, Biologics and other relevant Adjuvant analgesics (ex. antiepileptic and antidepressants used for pain relief).